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It is well known that the precipitation of solid cholesterol
2019-06-20
It is well-known that the precipitation of solid cholesterol monohydrate crystals from supersaturated bile is the first irreversible physical-chemical step in gallstone formation. To study the characteristics, metastable intermediates, and kinetics in the phase transitions of bile, a series of phase
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Undoubtedly hydroxyurea has a huge potential for improving
2019-06-20
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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Interpretation Patient centred medical education can
2019-06-20
Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei
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It is established that hypoxia can induce autophagy We evide
2019-06-20
It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 pak 4 after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections also indicates hyp
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br Material and methods br Results br Discussion
2019-06-20
Material and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Matching the morphology of paced complexes to tachycardia complexes is useful for mapping arrhythmias. In the atrium, pace mapping is useful for focal atrial arrhythmias in orde
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Missed cases have been reported
2019-06-19
Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although,
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br Introduction Percutaneous transcatheter device closure
2019-06-19
Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective
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Introduction Friedenstein was the first person
2019-06-19
Introduction Friedenstein was the first person to describe the isolation of clonogenic, proliferating fibroblastic MSCs from rat bone marrow (BM). And they showed that colony-forming unit fibroblasts (CFU-Fs) derived stromal SF1670 can serve as feeder layers for the culture of heamatopoietic stem
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A structured inherited arrhythmia or heart disease clinic
2019-06-19
A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli
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It is generally agreed that a previous history of aborted
2019-06-19
It is generally agreed that a previous history of aborted cardiac arrest, syncope, presence of a spontaneous type-1 ECG, and male gender are significant predictors of further arrhythmic events [5,7,10,11,32,33]. Risk stratification Exercise testing Some clinical studies have reported the augm
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br Remote monitoring advantages br What is obtained by
2019-06-19
Remote monitoring advantages What is obtained by remote monitoring? How should we act? Important factors at the time of informed consent Patients benefit greatly from RM, and they feel secure and safe because they feel connected to the hospital at all times. However, patients may have exces
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Lymphocytic infiltrates in thyroid cancer may suggest a back
2019-06-19
Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod
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We observed a downregulation of
2019-06-19
We observed a downregulation of several thyroid-related genes such as DUOX1, DUOX2, TG, and TSHR. This may appear counterintuitive given that dedifferentiation typically worsens patient outcomes. However, it is noteworthy that there was no difference in the Compstatin Supplier of SLC5A5 (sodium-iod
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br Material and methods br Results Thirty one patients were
2019-06-19
Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo
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buy SCH772984 HCl Bien templada en fin entre sus numerosas
2019-06-19
Bien templada, en fin, entre sus numerosas fuentes de conocimiento, sor Juana es tan pitagórica como san Agustín, Boecio o Gaffurio; foguea su neoplatonismo en ideas de Sinesio, Jámblico o Ficino, y buy SCH772984 HCl la vez está en posibilidad de compulsar sus adquisiciones teóricas sobre música en
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