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br INTRODUCCI N Con la incorporaci n de los
2019-05-23
INTRODUCCIÓN Con la incorporación de los derechos colectivos de los pueblos indígenas en la normatividad internacional de los derechos humanos, se inicia una nueva etapa en la conflictiva relación entre las bases fundacionales del poder político moderno y la diversidad cultural, en tanto aquellas
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src inhibitor Este reconocimiento marca un rasgo distintivo
2019-05-23
Este reconocimiento marca un rasgo distintivo de la reticente postura de Daniel Mato src inhibitor adoptar el nombre de ecl como campo de estudio. De manera consecuente, la mitad de las secciones de la antología están abocadas a la reflexión sobre los estudios culturales, el culturalismo, la crítica
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Pharmacological inhibition of PI K induces apoptosis of CLL
2019-05-23
Pharmacological inhibition of PI3Kα induces apoptosis of CLL pde inhibitors in vitro [5,18], and inhibits CLL migration towards CXCL12 [5]. The PI3Kα/δ inhibitor copanlisib induces significantly greater apoptosis of CLL cells compared to idelalisib (IC50 of 450nM and >10μM, respectively) in vitro a
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br Materials and methods The study
2019-05-23
Materials and methods The study was designed as an open label, single institution phase I study at the National Heart, Lung, Blood Institute, National Institutes of Health and was approved by Institutional Review Board (NCT01629082). All patients signed an informed consent prior to enrollment and
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There are a number of reasons for this disparity people
2019-05-23
There are a number of reasons for this disparity: people with disabilities are disproportionately poor, lacking in access to education and employment, and excluded from social networks. Health-care facilities, equipment, and transportation are often inaccessible. But another significant factor is th
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c-Myc Peptide Further complicating matters is that although
2019-05-23
Further complicating matters is that although menopause can increase serum BTMs, other normal physiological conditions, certain disease states, and drugs are also associated with elevated BTM concentrations [81–83]. Low body-mass index (BMI) is a risk factor for low bone density [84] and evidence ha
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Como tercera cuesti n y de
2019-05-22
Como tercera cuestión, y de suma relevancia, la economía argentina fue receptora de una muy pequeña inversión china, contrariamente Mouse FGF21 / Fibroblast Growth Factor 21 Protein (His Tag) la expectativa generada por la visita al país del presidente Hu Jintao, en noviembre de 2004. Se había supu
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BMS 309403 The combination therapy was exceedingly well tol
2019-05-22
The combination therapy was exceedingly well tolerated without any side effects to either drug. Remarkably, despite an advanced PV-stage the JAK2V617F allele burden was rapidly lowered from 90% mutated BMS 309403 at referral to 59% at 6 months, 28% at 10 months and 12% at 16 months of therapy (Fig
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The data also revealed notable
2019-05-22
The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone dna-pkcs detection; however, patients in Germany were most likely to have
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El ansia renovadora que suscita tambi n se crea
2019-05-22
El ansia renovadora que suscita también se crea y re-crea en los paratextos ilustrados, que en cierto modo también sugieren una performatividad discursiva aplicada a la realidad convulsa de México en la revista Futuro, que puede observarse en la imagen y que se ha titulado, “Defensores del orden”.
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br Discussion A familial platelet disorder
2019-05-22
Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).
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The PAX gene encodes a transcriptional factor
2019-05-22
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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br Discussion Studies have reported that permanent PMI using
2019-05-22
3. Discussion Studies have reported that permanent PMI using the conventional pectoral approach is impossible or contraindicated in 1–6% of patients [1–5]. In such patients, PMI via the iliac vein is considered an effective alternative. The advantages of this approach are that the wound size and
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Como se ha apuntado posteriormente la
2019-05-22
Como se ha apuntado posteriormente, la poesía como caminata es otra imagen de la búsqueda acerca de los límites del ser y del estado de ser ( y ). Las conexiones entre los procedimientos literarios y los del narrador-caminante de se presencian AG-14361 través de varios términos técnicos que se usan
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br A tactical change in research and
2019-05-22
A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di
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