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hydroxychloroquine sulfate br Long term maintenance of
2018-11-12
Long term maintenance of hPSCs in a scalable and defined suspension culture system A report published recently in Stem Cell Research (Chen et al., 2012, 8:388–402) extends from these previous studies to demonstrate for the first time, the long term expansion of hESCs retaining the characteristic
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A series of studies have
2018-11-12
A series of studies have demonstrated that GABAergic neurons were found to be affected in AD patients (Inaguma et al., 1992; Mikkonen et al., 1999; Takahashi et al., 2010), as well as cholinergic neurons and glutamatergic neurons (Danysz et al., 2000; Muir et al., 1994; Selkoe, 2002). However, some
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The second most stable reference
2018-11-12
The second most stable reference gene in the present study comparing OA- and healthy BMSCs is IPO8. The IPO8 gene product is a member of the importin-β family responsible for the nuclear import of proteins (Dean et al., 2001). Furthermore, it is involved in cytoplasmic miRNA-guided gene silencing an
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br Materials and methods br Results br
2018-11-12
Materials and methods Results Discussion Attempts to identify a resident adult stem cell in the kidney have led to the identification of CD133+/CD24+ cells in the Bowman\'s capsule (Sagrinati et al., 2006) or CD133+ cells in the renal cortex (Bussolati et al., 2005) and in the renal inner m
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V ATPases is a pH regulator in acidic subcellular compartmen
2018-11-12
V-ATPases is a pH regulator in acidic subcellular compartments including the Golgi complex, vesicles, and lysosomes. Wnt3a secretion requires its binding to the carrier protein wntless (WLS) and Wls-dependent secretion of Wnt3a was shown to require vacuolar acidification (Coombs et al, 2010). In the
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We show that the PB transposon and its
2018-11-12
We show that the PB transposon and its transposase are functional and quite efficient in terms of stable gene transfer to primary mesoangioblasts when compared to the transfection of plasmid vectors. Transposition occurred even when using large transposons comprising two expression cassettes and a s
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br Methods and materials br Results br Discussion Existing m
2018-11-12
Methods and materials Results Discussion Existing methods for hPSC differentiation to endothelial progenitors require the addition of growth factors and/or xenogenic components, limiting their application for large-scale production and therapeutic applications (Bautch, 2011; Wilson et al.,
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Living systems are constantly in motion and a changing
2018-11-12
Living systems are constantly in motion, and a changing magnetic field (MF) is associated with a changing electric field (EF). This has been shown via Faraday\'s Law, which states that a MF will interact with an electric circuit to produce an electromotive force. Endogenous pulsed EMF arises from th
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The finding that CD NGFR cells
2018-11-09
The finding that CD44+NGFR+ cells isolated from both surface and crypt sites contain most of the clonogenic progenitor activity in 2D assays and are also highly enriched in their content of these cells indicates that they are also biologically similar. This finding was further supported by the demon
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br Results Disease modeling using iPSCs can
2018-11-09
Results Disease modeling using iPSCs can be confounded by phenotypic variation resulting from genetic differences between individual iPSC lines (Merkle and Eggan, 2013). To overcome this obstacle, we sought to generate isogenic cell lines by targeted correction of the point mutation in the SOD1 i
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While there are several in vitro models for studying the
2018-11-09
While there are several in vitro models for studying the biomechanics of neural tissue (Morrison et al., 2011), to our knowledge, no previous studies have attempted a direct comparison of gene expression between in vivo transplanted and in vitro cultured dihydrofolate reductase inhibitor to investi
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Moreover one of the present work goals
2018-11-09
Moreover, one of the present work goals was to check the accuracy of PC plasma parameters calculations for real discharges by using analytical expressions obtained in Ref. . In the present paper, the same notation symbols are used as used in Ref. : are ionization and attachment frequencies; is an i
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br This result is not unexpected
2018-11-09
This result is not unexpected, as the Crocco Eq. (3) is equivalent to a canonical system. A similar result is obtained when splitting series in the case of the Blasius equation: which is not connected to any variational problems. Furthermore, let y be and the split linear system takes the form
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br Methods br Results The analyses indicate how microscale p
2018-11-09
Methods Results The analyses indicate how microscale pedestrian environment features varied by block group median income and race/ethnicity (Table 2). In all three regions, the findings revealed that XL184 certain microscale pedestrian features were less favorable (i.e., lower quality or absen
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Table shows the results of
2018-11-09
Table 2 shows the results of the multivariable linear regression. Briefly, in crude analyses (adjusting only for urinary creatinine) individuals in the 3rd and 4th quartiles of urinary MEHP had statistically significantly longer LTL compared to the lowest referent quartile (Table 2, Model 1) with ev
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