• br Adverse events Treatment reported toxicities were similar

  2019-06-13

  

  Adverse events Treatment reported toxicities were similar to those previously reported [23]. Discussion Several other studies have addressed the same issue using different bisphosphonates. The SABRE study randomised breast cancer patients taking anastrozole with a T-score of between −1 and −2

• March marked annual World TB Day this year s

  2019-06-13

  

  March 24 marked annual World TB Day, this year\'s theme being “reach the 3 million” who acquire tuberculosis every year but who do not get diagnosed, treated, or cured. Why do so many patients with this life-threatening infectious disease go under the radar? One reason, as Madhukar Pai and colleague

• The region is also suffering from administrative negligence

  2019-06-13

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

• Climate change will have far reaching effects on how we

  2019-06-13

  

  Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe

• However despite the strength of the research

  2019-06-13

  

  However, despite the strength of the research by Shawar and colleagues, any given process tracing case study can always be improved. In relation to this Article, the empirical tracing of causal processes could be strengthened further in future research, in particular by telling us more explicitly wh

• mitotic inhibitors Los dedos son las cuatro mil

  2019-06-13

  

  Los dedos son las cuatro mil verdades vistas por los ojos de las moscas. La labor del escritor, entonces, se pone mitotic inhibitors la altura de la labor del detective: encontrar los diez dedos, descubrir el cuerpo flotando en el agua, dar con una cabeza que yace en el fondo de un río y nombrarla p

• Y es que en Estados Unidos el campo

  2019-06-13

  

  Y es que, en Estados Unidos, el campo denominado Cultural Studies producía una gran cantidad de investigaciones sobre la región mediante categorías de análisis propias del llamado primer mundo. En su versión latinoamericana, los Estudios Culturales llegaron interleukin 2 receptor consolidarse en los

• br Acknowledgements br Introduction The

  2019-06-13

  

  Acknowledgements Introduction The chronic myeloproliferative neoplasms (MPN) comprise a group of clonal stem cell disorders with a high prevalence of the JAK2 V617F mutation (JAK2+) causing excessive production of mature blood cells. Transformation to acute myeloid leukemia (AML) is seen in 2–

• br Role of the funding source br Contributions br Conflicts

  2019-06-12

  

  Role of the funding source Contributions Conflicts of interest Acknowledgments The authors would like to thank the patients who participated in this study and their families. The authors would also like to acknowledge the writing assistance of Stephen Mosley, Ph.D., of Knowledge Point 36

• br Conclusion br Authors contribution br Competing interests

  2019-06-12

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• HLA DR resulted highly expressed in the surface

  2019-06-12

  

  HLA-DR resulted highly expressed in the surface of immature DC (iDC) as well as in mature DC (48 h-DC) in both groups; this is possibly due to the chronic infection as previously observed in monocytes-derived DC from HIV+[17]. As expected, maturation and activation markers - CD40, CD80, CD83 and CD8

• annexin v br Conclusion Accumulating clinical data suggest t

  2019-06-12

  

  Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,

• The Cochrane review on exercise after lung resection identif

  2019-06-12

  

  The Cochrane review on exercise after lung resection identified three randomized trials involving 178 participants. The meta-analysis found that exercise capacity was statistically greater in the exercise training group compared to the control group following lung resection for NSCLC. No between-gro

• In patients who develop bone

  2019-06-12

  

  In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a

• br Methods The prevalence of various fractionation

  2019-06-12

  

  Methods The prevalence of various fractionation schedules was extracted from each of the final articles included in the review. Other relevant information, such as significant predictive factors for the use of single fraction pka inhibitor therapy, changes in the prevalence of fractionation sche

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