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In Antirrhinum floral organ identity genes include
2024-03-04
In Antirrhinum, floral organ identity genes include DEFICIENS (DEF) (Sommer et al., 1990) and GLOBOSA (GLO) (Trobner et al., 1992) required for petal and stamen identity (B-function), PLENA (P) required for stamen and carpel formation (C-function) (Bradley et al., 1993) and SQUAMOSA (SQUA) which is
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Additional support for a role of HMGN in enhancing DNA
2024-03-04
Additional support for a role of HMGN1 in enhancing DNA repair comes from studies of transcription-coupled repair (TCR) in human cells. Lesions in the template strand of DNA induced by UV light stall the movement of RNA polymerase II (RNAPII) and interrupt transcription. Removal of these transcripti
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Experimentally the ECD spectrum of showed three
2024-03-04
Experimentally, the ECD spectrum of 1 showed three ECD bands: positive ones at 260 and 200nm, and a negative one at 230nm (Fig. 4). Meanwhile, there is only one broad positive ECD band starting from 300nm in the ECD spectrum of 2. ECD spectra of 1 and its derivatives attracted great interest because
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br Method of literature search
2024-03-04
Method of literature search Disclosures Acknowledgment The authors thank and acknowledge Mrs. Jaini Parekh, BFA, for illustrating the diagram in Figure 1. An overview of angiogenesis Angiogenesis is a biological process through which there is the formation of new blood vessels from pre-
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serotonin chemical structure br Acknowledgments and Disclosu
2024-03-02
Acknowledgments and Disclosures Alzheimer's disease as a synaptic pathology Alzheimer's disease (AD) is a chronic neurodegenerative serotonin chemical structure disorder and the most common cause of dementia in the elderly. Progressive depositions of amyloid plaques and neurofibrillary tangles
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br Mortality and morbidity Alzheimer s disease is officially
2024-03-02
Mortality and morbidity Alzheimer's disease is officially listed as the sixth-leading cause of death in the United States [208]. It is the fifth-leading cause of death for those age 65 and older [198]. However, it cudc may cause even more deaths than official sources recognize. Alzheimer's is al
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AMPK is an essential player in
2024-03-02
AMPK is an essential player in adiponectin signaling pathway that regulates energy metabolism. The fact that suppression of AMPK activity by compound C largely diminished candesartan-mediated inhibition of NFκB via blocking AT1 also suggests that the AT1-mediated effect is at least partly resulted f
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While A Rs communicate mainly with the
2024-03-02
While A1Rs communicate mainly with the D1R subtype [36], A2AR and D2R interaction occurs mainly in basal ganglia. D2Rs colocalizes with A2ARs in this Pyrimethamine synthesis area where they are preferentially localized postsynaptically in the soma and dendrites of GABAergic striatopallidal neurons
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Introduction The lysosomal storage disorder Gaucher disease
2024-03-02
Introduction The lysosomal storage disorder Gaucher disease (Mendelian Inheritance in Man, OMIM #230800) results from the recessively inherited deficiency of lysosomal glucocerebrosidase (GCase, EC 3.2.1.45), caused by mutations in the gene GBA1 (MIM# 606463) located on chromosome 1q21. The enzymat
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In the final set of experiments the dependence
2024-03-02
In the final set of experiments, the dependence of the reaction rate on viscosity was determined. The experimental protocol previously used to study the reaction of LOX with AA was used., Reactions of 5-LOX and AA were carried out at different relative viscosities in Tris buffer (25mM, pH 8.0) at 2
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The overall mechanism of the Cdc complex resembles that
2024-03-02
The overall mechanism of the Cdc48 complex resembles that of the 19S regulatory subunit of the proteasome, which also uses receptor proteins to bind polyubiquitin chains attached to a substrate and employs a translocation mechanism (for review, see Kish-Trier and Hill, 2013). As with Cdc48, full sub
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br Experimental protocols br Results and
2024-03-02
Experimental protocols Results and discussion Conclusion 15-LOX-1 is an important mammalian lipoxygenase which plays an important role in the biosynthesis of leukotrienes, lipoxins and other signalling molecules. These signalling molecules play a regulatory role in several respiratory disea
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LBH589 br Conclusions br Author declaration br Acknowledgeme
2024-03-02
Conclusions Author declaration Acknowledgements Introduction ASK1 scaffolding proteins ASK1 adaptor proteins Conclusions Scaffolding and adaptor proteins can coordinate the specific activation of a MAP3K-MAP2K-MAPK pathway in response to various stimuli. For example, both LBH589
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br Introduction Natural antioxidants in vegetables have gain
2024-03-01
Introduction Natural antioxidants, in vegetables, have gained the attention of both researchers and consumers. Vegetable amaranth (Amaranthus tricolor) is a good source of minerals, vitamins, phenolics, and carotenoids; it also contains betalains, a nitrogen containing group of natural pigments,
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It is worth noting that in S
2024-03-01
It is worth noting that in S. cerevisiae, the control of two cell-cycle checkpoints requiring Mcm1 involves two very different mechanisms. At the G1/S transition, Mcm1 transactivation activity is inhibited by Yox1 and Yhp1 repressors, whose expression is periodically regulated through the cell cycle
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