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Un tercer gui n si acaso
2019-05-14
Un tercer guión, si acaso el más inquietante de los tres, podría hallarse en la banda de cuatro críticos literarios consagrados cholesterol absorption inhibitor la obra de Archimboldi, el gran autor que Bolaño introduce en la novela 2666. La narración capta una muestra episódica del modo de inserció
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Equally important to the scientific findings of Soka and
2019-05-13
Equally important to the scientific findings of Soka and colleagues\' report is the context of the activities—established not as a research study but as a national programme oriented toward health service provision and risk reduction. The programme packaged semen testing with counselling for survivo
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tgf beta receptor br Conflict of interest statement
2019-05-13
Conflict of interest statement Acknowledgments The authors would like to thank Dr. Bjørn Naume, and Dr. Erik Løkkevik from the Department of Clinical Oncology, the Norwegian Radium Hospital for their helpful comments. This study was supported by grants from the Norwegian Radium Hospital Founda
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A number of clinical studies have
2019-05-13
A number of clinical studies have confirmed the beneficial effect of ranolazine in either prevention or treatment of AF. The first strong evidence was provided by MERLIN-TIMI 36 trial [the Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST-Elevation Acute Coronary Syndrome–Thrombolysis
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Cancer stem cells are capable of differentiation and self
2019-05-13
Cancer stem jnk inhibitors are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. CSCs p
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Different ideas however emerged in the s and
2019-05-13
Different ideas, however, emerged in the 1960s and 1970s in the minds of computational biologists interested in the theory of wave propagation in excitable media. Based on chemical [17] and numerical experiments, [18] scientists in the Soviet Union and the USA began to suggest that fibrillation was
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Elderly patients especially those in
2019-05-10
Elderly patients, especially those in excess of 70 years of age, are often quite fragile; such fragility may be secondary to aging or comorbidity. In this “susceptible” patient population, the negative influence of ET-adverse events on patient adherence to a medication regimen can be elevated. This
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Como ha destacado Leonardo Tarife o su obra
2019-05-10
Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac
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br Discussion Valproic acid is a potent
2019-05-10
Discussion Valproic Tasquinimod is a potent inhibitor of histone deacetylases (HDAC). It can modify the structure of chromatin allowing recruitment of transcription factors to restore epigenetically suppressed genes. Valproic acid has been shown to possess antiproliferative activity and to overco
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That well established data for Sapindaceae toxicity have
2019-05-10
That well-established data for Sapindaceae toxicity have long existed from clinical experience in Africa and the Caribbean is an important lesson for global health and neurotoxicology. A worldwide understanding of the adverse effects on the nervous system of both naturally occurring as well as synth
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br Conclusion br Source of funding br Acknowledgement
2019-05-10
Conclusion Source of funding Acknowledgement Arsenic is widely dispersed throughout nature, and its toxic effect in humans, which focus mainly on somatic cells, as well known. Epidemiological research and in vitro testing have shown that long-term contact with arsenic can induce the forma
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br is a bacterial infection causing necrotising lesions of
2019-05-10
is a bacterial infection causing necrotising lesions of skin and subcutaneous tissue. Widely known as Buruli ulcer, it is classified as a neglected tropical disease by WHO. If diagnosed and treated early, outcomes are good, but if left untreated it can progress to a severe disease resulting in hig
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GP ablation has been regarded as a vagal
2019-05-10
GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc
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Heart failure is a complex
2019-05-09
Heart failure is a complex disease and the status of each patient is highly heterogeneous; therefore, nominal manufacturer-delivered device settings may not be optimal for all patients who receive CRT implantation. A growing body of evidence suggests hemodynamic and clinical status benefits associat
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We conducted a retrospective analysis to compare a BMD alone
2019-05-09
We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at
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